Transcript levels of MacroH2A1, respective isoforms and splicing regulators were assessed by RT-qPCR in five PCa cell lines (22Rv1, LNCaP, VCaP, DU145 and PC-3) and normalized for a benign prostate cell line (RWPE-1) (Fig. 3a, b). The gene discussed is MACROH2A1; the disease is posterior cortical atrophy.