Thus, we used this compound to evaluate the impact of CaMKK2 inhibition on the growth of E0771, 4T1, and Met1 cell-derived tumors propagated in syngeneic hosts, as well as in the MMTV- PyMT spontaneous model of mammary carcinoma (Fig. 8a; Supplementary Fig. 10A–C). Here, CAMKK2 is linked to breast carcinoma.