Subsequently, we aimed to elucidate whether miR-328 in M2 macrophages is able to promote the pulmonary fibrotic process, so we injected untreated M2 macrophages or M2 macrophages infected with a lentivirus containing antagomir NC + scramble shRNA, antagomir miR-328 + scramble shRNA, antagomir NC + shRNA-FAM13A, or antagomir miR-328 + shRNA-FAM13A into rats in the PF group. Here, FAM13A is linked to pemphigus foliaceus.