Moreover, NSCLC patients with deep tumor invasion (T3/T4) and high AJCC 8th stage (stages III/IV) had higher expression of STYK1 than these with superficial tumor invasion (T1/T2) and low AJCC 8th stage (stages I/II) (P < 0.001, Fig. 1f). Here, STYK1 is linked to neoplasm.