After analyzing the total NSCLC group and the stratified LUAD and LUSC groups, Kaplan–Meier survival curves indicated that patients with low STYK1/high SPINT2 had the best prognosis, and patients with high STYK1/low SPINT2 had the worst prognosis (Fig. 6e–g). Here, STYK1 is linked to non-small cell lung carcinoma.