ANGPTL4 and metabolic syndrome: An investigation of the association between ANGPTL4 levels and metabolic parameters in a population based study, concentrations of ANGPTL4 were found to be positively related to the metabolic syndrome, and plasma ANGPTL4 concentrations were inversely related to LDL-C and HDL-C, but positively associated with serum triglycerides [45]. Other study showed that polymorphism within the ANGPTL4 gene is not related to metabolic components in white subjects [46].