AFP and neoplasm: In the univariate analysis, the significant factors were tumor size (HR = 3.739; 95% CI: 2.577–5.426; p <  0.001), TNM stage (HR = 4.396; 95% CI: 3.207–6.026; p <  0.001), treatment exposure (HR = 3.029; 95% CI: 2.195–4.181; p <  0.001), AFP (HR = 2.324; 95% CI: 1.727–3.128; p <  0.001), CRP (HR = 3.227; 95% CI: 2.376–4.381; p <  0.001), ALB (HR = 0.625; 95% CI: 0.465–0.841; p = 0.002), PCR (HR = 0.340; 95% CI: 0.244–0.473; p <  0.001), and ACR (HR = 0.315; 95% CI: 0.232–0.426; p <  0.001).