AFP and neoplasm: In the univariate analysis, the significant factors were tumor size (HR = 4.332; 95% CI: 2.896–6.482; p <  0.001), TNM stage (HR = 0.211; 95% CI: 0.152–0.293; p <  0.001), treatment exposure (HR = 3.005; 95% CI: 2.157–4.188; p <  0.001), AFP (HR = 2.297; 95% CI: 1.691–3.122; p <  0.001), CRP (HR = 3.378; 95% CI: 2.460–4.640; p <  0.001), ALB (HR = 0.665; 95% CI: 0.490–0.902; p = 0.009), PCR (HR = 0.323; 95% CI: 0.229–0.457; p <  0.001), and ACR (HR =0.302; 95% CI: 0.221–0.413; p <  0.001).