AFP and neoplasm: The 1-, 3-, and 5-year OS rate of the high ACR group were significantly higher than those of the low ACR group in tumor size < 5 cm subgroup (97.6, 85.0, 82.9% vs. 78.9, 47.8, 47.8%, respectively; p <  0.0001) (Fig. 4a), in early stage (stage Iand II) subgroup (94.5, 83.5, 81.9% vs. 74.4, 53.2, 53.2%, respectively; p <  0.0001) (Fig. 4c), in serum AFP level <  400 ng/mL subgroup (95.4, 79.8, 77.9% vs. 62.2, 40.8, 39.4%, respectively; p <  0.0001) (Fig. 4e), and in platelet / CRP <  47.8 subgroup (79.2, 61.0, 58.7% vs. 54.1, 34.9, 33.2%, respectively; p = 0.0007) (Fig. 4g).