Myelin oligodendrocyte glycoprotein antibodies (MOG-ab) have been identified in a range of acquired demyelinating syndromes in the pediatric population, including acute demyelinating encephalomyelitis (ADEM), optic neuritis (ON), and transverse myelitis (TM) [54,55,56,57]. The gene discussed is OMG; the disease is acute disseminated encephalomyelitis.