FLT3 and acute myeloid leukemia: In detail, in a phase II study enrolling relapsed/refractory FLT3-mutated AML patients, it was shown that the drug (dosage of 200 mg, three times/day continuously in 28-day cycles) was able to induce a CR with an incomplete count recovery (CRi) in 23% of FLT3/tyrosine kinase inhibitor (TKI) naïve patients, and in 5% of patients previously treated with other FLT3 inhibitors [28].