In continuation of our previous work aimed at developing such synthetic indolizine analogues as enoyl-[acyl-carrier] protein reductase enzyme inhibitors (Fig 2), we undertake the screening of substituted 7-methoxy-indolizine analogues (Fig 3) to determine their whole-cell anti-TB properties against H3Rv and MDR strains of MTB using the resazurin microplate assay (REMA) plate method. The gene discussed is FASN; the disease is tuberculosis.