MMP2 and neoplasm: Our data suggested that salidroside dose‐dependently suppressed tumor volume and weight (Figure 5A and 5B), increased cell apoptosis (Figure 5C), reduced diffuse metastatic infiltration of BxPC‐3 cells in the lung tissues (Figure 5D), and significantly abrogated expression of HIF‐1α, LOXL2, MMP2, and MMP9, while enhanced E‐cadherin in tumor tissue (Figure 5E and 5F), suggesting the antigrowth and antimetastatic effect of salidroside in vivo.