EBP and central nervous system cancer: To date, it is believed that activation of EBP increases the proliferation of human lymphocytes, fibroblasts, melanoma, astrocytoma, glioma, and endothelial cells (Péterszegi et al. 1996; Tajima et al. 1997; Jung et al. 1998; Hinek et al. 1999; Dutoya et al. 2000; Devy et al. 2010).