These findings collectively refute the hypothesis of a single point of origin in the transition zone and instead suggest that NF2-associated vestibular schwannomas are often comprised of numerous smaller lesions along the length of the nerve which have coalesced into a large multi-nodular mass, possibly explaining the greater aggressiveness and risk of recurrence of NF2-associated vestibular schwannomas. The gene discussed is NF2; the disease is Vestibular schwannoma.