Whilst, the expression of KDM5A (p = 0.001), KDM5B (p = 0.047), LSD2 (p = 0.002), FBXL10 (p = 0.0001) and KDM5C genes was augmented in ccRCC and data were statistically significant except KDM5C (p = 0.062; Fig. 5c–g). This evidence concerns the gene KDM5C and nonpapillary renal cell carcinoma.