In mice with wild type P-selectin (SelpWTRag2−/−), M-CSCs quickly disseminated throughout the peritoneal cavity after orthotopic or i.p. injection (Fig. 3g, h) with visible tumor nodules growing on the omentum, mesenteries and small bowels (Fig. 3g, h) and developed massive ascites (Supplementary Table 4). The gene discussed is SELP; the disease is neoplasm.