RACGAP1 and liver cancer: Mechanistically, RACGAP1P works as a ceRNA to compete with miR-15a-5p for binding to the 3’UTR region to relieve the inhibitory effects of miR-15a-5p on RACGAP1 expression, whereas MRE mutations impair the regulation of RACGAP1 by RCGAP1P. These findings provide strong evidence in support of a key role for RACGAP1P in the tumourigenesis of liver cancer.