ROBO4 and congenital diaphragmatic hernia: When Zhang et al. [40] studied the etiology of congenital diaphragmatic hernia (CDH), N-deacetylase-N-sulfotransferase-1ECKO (Ndst1ECKO) mice showed similar vascularization defects in the diaphragm to Slit3−/− mice and showed more severe defects in angiogenesis when the Robo4 gene was knocked out simultaneously.