NOS3 and Reduced sperm motility: Previous studies have shown that the exonal single nucleotide polymorphism (SNP) rs1893316 in cation channel of sperm associated 1 (CATSPER1), tektin-t (R207H) gene polymorphism, prostate and testis 1 (PATE1) variant (A1423G), endothelial nitric oxide synthase (eNOS) (Glu298Asp) gene polymorphism may be associated with asthenozoospermia risk [4–7].