In a recent study comparing the matrsiome of MDA-WT and MDA-Lung tumour xenografts (63), MMP1 and THBS2 were detected uniquely in MDA-WT tumours and AGRN was detected uniquely in MDA-Lung tumours, which correlates with our proteomics data of MDA-WT and MDA-Lung secretomes. This evidence concerns the gene THBS2 and neoplasm.