PCSK1 and type 2 diabetes mellitus: Performing comparative analysis of the healthy and T2D networks, all pairwise correlations were highly similar under healthy and T2D conditions (example of BMP5 and PCSK1, Fig. 6c, d), which is remarkable considering that the data come from different donors and are subject to inter-individual variability as well as several confounding factors (e.g., age and weight).