Compared to that in normal tissue, CKAP4, DUSP1, PAX8, NOTCH3, C-KIT and AP1M2 were upregulated in tumor tissue, while ADRB3, ANG, BTG2, ESD, ST13, ST7L, RAD51, DUSP4 and FBXL7 were highly downregulated in tumor tissue. The gene discussed is FBXL7; the disease is neoplasm.