Thus, we have included the analysis of 15 HR genes, which are frequently mutated in hereditary cancer (ATM, BARD1, BRCA1, BRCA2, BRIP1, CHEK1, CHEK2, MRE11A, NBN, PALB2, PTEN, RAD50, RAD51B, RAD51C, RAD51D). The gene discussed is CHEK1; the disease is hereditary cancer.