Thus, we have included the analysis of 15 HR genes, which are frequently mutated in hereditary cancer (ATM, BARD1, BRCA1, BRCA2, BRIP1, CHEK1, CHEK2, MRE11A, NBN, PALB2, PTEN, RAD50, RAD51B, RAD51C, RAD51D). The gene discussed is MRE11; the disease is hereditary cancer.