Since the authors were interested in studying CELF1 mediated AS events in three pre-mRNAs (COL16A1, TACC2 and ITGA6) known to play a role in cell growth, they found a modest difference in the expression for COL16A1, TACC2, and ITGA6 CELF1-mediated splicing events in HNSCC tumors in comparison to normal samples. Here, COL16A1 is linked to head and neck squamous cell carcinoma.