IL6 and obstructive sleep apnea syndrome: The IL-6 amplifier is also thought to be associated with a number of diseases and disorders [81,82,83] as well as cardiovascular diseases, including atherosclerosis, in patients with OSA, since IH activates both NF-κB (via hypoxic conditions) and STAT3 (via increased IL-6) [34,35,43,61,83].