Although miR-150 repressed Akt rather than p27Kip1 in our results, miR-150 inhibits p27Kip1 directly by binding to the 3′ UTR of p27Kip1 mRNA in other diseases such as prostate cancer [42], which shows the tissue-specific nature of miR expression. The gene discussed is AKT1; the disease is prostate carcinoma.