In a recent study, miR-29c, miR-200c, and miR-93 3 were reported to regulate cell proliferation of leiomyoma via their effects on key cell cycle regulatory proteins including E2F transcription factor 1(E2F1), Cyclin D1 (CCND1), and CDK2 in vitro [20]. Here, E2F1 is linked to leiomyoma.