MTSS1 and neoplasm: Another ΔNp63 target gene potentially involved in breast tumor progression is the Metastasis Supressor 1 (MTSS1), also known as Missing in Metastasis, or MIM or BEG4. MTSS1 is a gene involved in the regulation of actin-based cytoskeleton organization, whose tumor-related function is controversial, since it might act as pro-or anti-metastatic factor, depending on the tumor context [93,94,95].