CHRNE and ophthalmoplegia: 2005), which therefore require fast AChR recovery rates for efficient neuromuscular transmission. In patients with null mutations of the CHRNE gene (coding for the ε‐subunit) (Ealing et al. 2002; Engel et al. 2015), neuromuscular transmission has to depend on the fetal AChR, and one major symptomatic feature of these patients is ophthalmoplegia.