AFF1 and leukemia: According to the report, the nine most frequent fusion partners of MLL are AF4 (∼36%), AF9 (∼19%), ENL (∼13%), AF10 (∼8%), PTD (∼5%), ELL (∼4%), AF6 (∼4%), EPS15 (∼2%), and AF1Q (∼1%), which together represent more than 92% of the MLL-FPs found in MLL-r leukemia patients (Meyer et al., 2018).