Let us consider the spatial variables x and y as well as the temporal variable t, we simulate the evolution of the epidermal growth factor (EGF, eg(x, y, t)) and three populations of cells: proliferationg tumor cells (cp(x, y, t)), quiescent tumor cells (cq(x, y, t)), and immune effector cells (i(x, y, t)). The gene discussed is EGF; the disease is neoplasm.