It mediates AU-rich element mRNA degradation and as a resolvase for G-quadruplex DNA in vitro (78, 79). It involves in TERT stabilization and Correction of the positioning of the template domain of hTERT (80), it also Regulates p53 Pre-mRNA 3′-End Processing Following UV-Induced DNA Damage (81) and Prevents migration of colon cancer cells (82). The gene discussed is TP53; the disease is malignant colon neoplasm.