Laboratory examination revealed thrombocytopenia and Coombs-negative hemolytic anemia (hemoglobin 3.7 mmol/L, platelets 118 × 109/L, haptoglobin < 0.1 g/L, fragmented erythrocytes 1%, lactate dehydrogenase > 13 mmol/L) but normal ADAMTS13 levels and activity (>50%) and absence of ADAMTS13 autoantibodies. The gene discussed is ADAMTS13; the disease is Thrombocytopenia.