RHOA and gastric cancer: As shown in Supplementary Figure S2, most of the publications were assigned to term #1, “activation of invasion and metastasis.” In GC, this hallmark term associates with RHOA, in signal pathways (Chiou et al., 2001; Murray et al., 2008; Bennett et al., 2011; Zhou et al., 2011; Gomes et al., 2013).