Epigenetically, GC cell invasion was suppressed by the non-coding RNA, miR-647, through a RHOA-mediated SRF/MYH9 axis (Ye et al., 2017), while miR-29, in association with chemotherapy, inhibited GC cell invasion and migration, in vitro and in vivo (Wang et al., 2015). The gene discussed is RHOA; the disease is gastric cancer.