We noticed that previously reported transcripts with aberrant levels in HCC such as mRNAs (PLOD3, SF3B4, ADH4, and COLEC10), lncRNAs (HULC and SNHG7), and miRNAs (miR-421 and miR-761) were also identified in our RNA-seq (Figure 1C; Panzitt et al., 2007; Wang et al., 2010; Wei et al., 2012; Zhang et al., 2012; Li G. et al., 2015; Zhou et al., 2016; Shen et al., 2018; Zhang and Wu, 2018). This evidence concerns the gene PLOD3 and hepatocellular carcinoma.