NFKBIZ and psoriasis: In addition, IκBζ is directly recruited to the promoter regions of psoriasis-associated target genes (167) whereas the loss of IκBζ expression alters H3K4 tri-methylation and switch/sucrose non-fermenting (SWI/SNF) complex recruitment, thereby influencing promoter accessibility at IκBζ target genes (168, 169).