P3 pDCs and Axl+ DCs may account for the cDC-like functions of pDCs during infection, namely viral transfer and cross-presentation and production of pro-inflammatory cytokines—upon TLR7 stimulation, Axl+ DCs are able to produce IL-12 but not pDCs, and it is unclear whether P3 activated pDCs are also capable of this function alongside their potential for T cell stimulation. The gene discussed is TLR7; the disease is infection.