CCL21 and metabolic dysfunction-associated steatohepatitis: Using PDPN to label lymphatic vessels we found that the number of lymphatic vessels that had CCL21hi/+ expression was about 4 vessels per mm2 in non-diseased livers, while the frequency of lymphatic vessels with high expression of CCL21 was between 6 and 10 vessels per mm2 in patients with HCV and NASH (Figure 2C).