IL13 and metabolic dysfunction-associated steatohepatitis: While IL13 expression was not detected in any of the cell types we evaluated, suggesting a signal strength issue; CD36, FABP4 and TFF3, genes that are targets of IL13 signaling, were upregulated (53–55), and ATF3, which inhibits IL13 transcription (56), was downregulated in LECs from NASH livers (Figure 5A).