CD8A and melanoma: We have shown previously that VLPs derived from the bacteriophage Qβ loaded with A-type CpGs and coupled to MelanA/MART-1 peptide can be efficiently processed by murine and human DCs for MHC-I presentation and induced strong CD8+ T-cell responses in HLA-A2 transgenic mice as well as in melanoma patients (17, 18).