GAPDH and HIV infectious disease: Although macaques might differ from humans in having as yet unrecovered replication-competent PcEV loci, levels of cell-associated HERV-K(HML2) transcription appear similar: ~30 copies/1,000 copies GAPDH in PBMC of non-acute HIV infection cases and ~15 RNA/1,000 copies GAPDH in PBMC from uninfected individuals (13).