MFN2 and neuropathy: CMT2A is a subtype of an incurable neuropathy, Charcot-Marie-Tooth (CMT), characterized by progressive distal weakness, muscular atrophy, and sensory abnormalities, affecting 1 in 2,500 people (Tazir et al., 2013, 2014; El-abassi et al., 2014; Stuppia et al., 2015; Stojkovic, 2016; Barbullushi et al., 2019).