GFAP and amyotrophic lateral sclerosis: Interestingly, glial fibrillary acidic protein (GFAP)-positive and negative glial cells in the cerebellum of C9-ALS and C9-FTLD cases (Gendron et al., 2013) and induced pluripotent stem cell (iPSC)-derived astroglia have also been confirmed to contain sense foci (Sareen et al., 2013).