-↑S100A9 in familial and sporadic AD patients (Shepherd et al., 2006);-↑S100A9 expression in brain lysates of AD patients (Kummer et al., 2012);-↑S100A9 expression in Tg2576 mice and AD patients (Chang et al., 2012);-↑S100A9 expression in cortex and hippocampus of CT-Tg and Tg2576 mice model and in AD brain patients (Ha et al., 2010);-S100A9 in plaques of hippocampal and neocortical areas of AD patents in Braak stages III to VI (Wang C. et al., 2014). The gene discussed is S100A9; the disease is Alzheimer disease.