HLA-C and ICF syndrome: The greatest enrichments were found for “deletion or duplication of chromosome 7q11.23,” “immunodeficiency, centromeric instability and facial abnormalities (ICF) syndrome,” “asthma,” “down syndrome,” and “human immunodeficiency virus.” Notably, though several of these relate to immune function, none of the probes driving these enrichments were within the CoRSIV-rich MHC region on chromosome 6.