It is revealed that adiponectin produces asthma symptoms mainly through the oxidative stress pathway, and its declining level will aggravate the asthma.19 In this study, it was found that the leptin level in observation group was obviously lower than that in control group, leptin was positively correlated with the disease grade, and leptin was one of the risk factors for asthma in children. The gene discussed is ADIPOQ; the disease is asthma.