Overall, M(IFNγ + LPS) derived from BD-L secreted less pro-inflammatory cytokines compared to controls (IL-1β, p = 0.002; TNFα, p = 0.002; and IL-6, p = 0.003) and BD-E (IL-1β, p = 0.010; TNFα, p = 0.021; and IL-6, p = 0.028) (Figs. 2, 3, 4). This evidence concerns the gene TNF and Behcet disease.