However, we found that dietary iron restriction, with concomitant anemia did not produce a further rise in RVSP in fpnC326Yfl/fl SMMHC-CreERT2+ mice, demonstrating that PASMC iron deficiency fully explains the effects of systemic iron deficiency on the pulmonary vasculature (SI Appendix, Fig. S5). Here, MYH11 is linked to Iron deficiency anemia.