INS and type 2 diabetes mellitus: Fasting blood glucose (11.3 ± 0.7 mmol/L vs. 5.2 ± 0.2 mmol/L, p < 0.001), insulin concentration (5.7 ± 1.4 μIU/mL vs. 0.6 ± 0.3 μIU/mL, p < 0.001) and bodyweight (356 ± 8 g vs. 291 ± 4 g, p < 0.001 was higher in animals with than without T2DM.