ABCC1 and Familial prostate cancer: It was found that 6-gingerol, 10-gingerol, 6-shogaol, and 10-shogaol showed an antiproliferative effect on human prostate cancer cells via a downregulation of the protein expression of multidrug resistance associated protein 1 (MRP1) and glutathione-S-transferase (GSTπ) [59].