Moreover, circulating or microparticle-bound mCRP has been found to be a better diagnostic index than pentameric CRP in myocardial infarction [131,161] and peripheral artery disease [142] using homemade assays; for example, an ELISA assay designed for quantifying plasma mCRP based on commercially-available reagents [162] may be a promising tool for evaluation of mCRP in plasma. The gene discussed is CRP; the disease is peripheral arterial disease.