These findings are similar to other studies that found an association for the co-occurrence of PTEN and CDKN2A deletions [7,33] and/or TP53 and CDKN2A alterations in gliomas [15,51], while concomitants TP53 and PTEN alterations were less frequent [7,52,53]. The gene discussed is CDKN2A; the disease is central nervous system cancer.