Substantial evidence indicated patients with PCOS had a dysregulated expression of angiogenic factors in their endometrium, including vascular endothelial growth factor (VEGF), angiopoietins, platelet-derived growth factor (PGF), transforming growth factor-β (TGF-β), and some basic fibroblast growth factors [10]. The gene discussed is VEGFA; the disease is polycystic ovary syndrome.