The 13 overexpressed genes were reported to play a role in RCC: PAX2, NAT8, GBA3, SLC22A2 [38–43] other cancer types: AOC1, HAO2, TMEM27 [44–47], cell death (NPR3 [48]) or kidney metabolism: TMEM171, CYS1 [49,50]. The gene discussed is HAO2; the disease is cancer.